| Conference | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| # | Western Conference | MP | W | D | L | G | GD | Pts | Form |
| 1. | Vancouver Whitecaps | 15 | 9 | 4 | 2 | 37:17 | 20 | 31 | |
| 2. | Seattle Sounders | 15 | 8 | 6 | 1 | 36:20 | 16 | 30 | |
| 3. | Los Angeles FC | 15 | 9 | 2 | 4 | 28:13 | 15 | 29 | |
| 4. | Colorado Rapids | 16 | 8 | 3 | 5 | 23:19 | 4 | 27 | |
| 5. | Portland Timbers | 16 | 7 | 6 | 3 | 25:22 | 3 | 27 | |
| 6. | San Diego FC | 17 | 7 | 5 | 5 | 25:17 | 8 | 26 | |
| 7. | Real Salt Lake | 16 | 8 | 1 | 7 | 22:21 | 1 | 25 | |
| 8. | Minnesota United | 16 | 7 | 4 | 5 | 26:20 | 6 | 25 | |
| 9. | Austin FC | 15 | 6 | 7 | 2 | 16:13 | 3 | 25 | |
| 10. | FC Dallas | 16 | 5 | 3 | 8 | 23:24 | -1 | 18 | |
| 11. | Houston Dynamo | 16 | 5 | 3 | 8 | 18:26 | -8 | 18 | |
| 12. | San Jose Earthquakes | 16 | 4 | 6 | 6 | 35:31 | 4 | 18 | |
| 13. | Los Angeles Galaxy | 15 | 5 | 2 | 8 | 23:26 | -3 | 17 | |
| 14. | St. Louis City | 16 | 4 | 5 | 7 | 21:26 | -5 | 17 | |
| 15. | Sporting Kansas City | 16 | 4 | 4 | 8 | 25:32 | -7 | 16 | |
| # | Eastern Conference | MP | W | D | L | G | GD | Pts | Form |
| 1. | Charlotte | 16 | 12 | 1 | 3 | 31:16 | 15 | 37 | |
| 2. | Philadelphia Union | 16 | 11 | 4 | 1 | 35:15 | 20 | 37 | |
| 3. | Nashville SC | 16 | 11 | 3 | 2 | 34:12 | 22 | 36 | |
| 4. | New York City | 16 | 11 | 0 | 5 | 27:19 | 8 | 33 | |
| 5. | New York Red Bulls | 16 | 10 | 3 | 3 | 36:22 | 14 | 33 | |
| 6. | Inter Miami | 14 | 9 | 3 | 2 | 33:20 | 13 | 30 | |
| 7. | Columbus Crew | 16 | 8 | 5 | 3 | 26:19 | 7 | 29 | |
| 8. | Orlando City | 15 | 8 | 3 | 4 | 34:23 | 11 | 27 | |
| 9. | FC Cincinnati | 16 | 8 | 3 | 5 | 24:19 | 5 | 27 | |
| 10. | Chicago Fire | 16 | 6 | 5 | 5 | 23:23 | 0 | 23 | |
| 11. | Atlanta Utd | 16 | 4 | 7 | 5 | 28:28 | 0 | 19 | |
| 12. | New England Revolution | 16 | 4 | 3 | 9 | 18:23 | -5 | 15 | |
| 13. | Toronto FC | 16 | 2 | 7 | 7 | 13:17 | -4 | 13 | |
| 14. | DC United | 16 | 2 | 7 | 7 | 13:30 | -17 | 13 | |
| 15. | CF Montreal | 16 | 2 | 5 | 9 | 13:32 | -19 | 11 | |